Spryng Clinical Data

Histopathologic characterization and persistence of an intra-articular hydrogel in rhesus macaques with naturally occurring osteoarthritis

Julie Majka, DVM, M.S, Heather Simmons, DVM, DACVP, Puja Basu, DVM, PhD, DACVP, Jennifer Coonen, DVM, DACLAM, Kirsty Husby, DVM, DACVS-LA, MBA, Saverio Capuano III, DVM, DACLAM

Improved mobility following intra-articular collagen-elastin hydrogel therapy in geriatric rhesus macaques with naturally occurring osteoarthritis

Julie Majka, DVM, M.S, Jennifer Coonen, DVM, DACLAM, Nicholas Keuler, M.S., Kirsty Husby, DVM, DACVS-LA, MBA, Heather A, Simmons, DVM, DACVP, Puja Basu, DVM, PhD, DACVP, Jennifer M, Hayes, Ricki Colman, PhD, Saverio Capuano III, DVM, DACLAM



Intra-articular hydrogel therapeutics exhibit anti-inflammatory effects on cytokine-stimulated equine cartilage and synovial membrane explants

Erica Secor, DVM, PhD, DACVS, Matthew Thomas, BS, Emma Chu, BS, Sarah Hazzard, BS, Sara Raimondi, BS, Heidi Reesink, VMD, PhD, DACVS

Evaluation of intra-articular injection of collagen-elastin hydrogel microparticles for managing osteoarthritis-associated elbow pain in dogs: a double-blind, positive-controlled clinical trial

Gabriella Castro, Lindsay Hochman Elam and Felix Michael Duerr


The Effect of Collagen-Elastin Hydrogel Microparticles (CEHM) on Pain and Function Secondary to Hip Osteoarthritis in Dogs

Principal investigators:
Alex Amalfitano, DVM
James Gaynor, DVM, DACVA, DACVPM
Samuel Stewart,
DVM, DACVECC


Evaluating the benefit and tolerability of an intra-articular injection of a collagen-elastin hydrogel micro particle (CEHM) into the stifle joint of dogs with suspected cruciate ligament rupture

Principal investigators:
Samuel Stewart, DVM, DACVECC
Chris Thomson, DVM, DACVS-SA
Erik B. Kleeman,
DVM, MPH


Spryng Canine Poster Presentation 2023 ACVS Surgery Summit


Clinical Study Assessing the Tolerance of Spryng Administration in Dogs

Principal investigators:
Shawn Koslov, DVM, MS
Stephanie Starek, LVT
Ann Zieser,
DVM


Clinical Study Assessing the Tolerance of Spryng Administration in Cats

Principal investigators:
Shawn Koslov, DVM, MS
Stephanie Starek, LVT
Ann Zieser,
DVM


Tolerability of Intra-articular Administration of Spryng in the Hindlimb Joints of Horses

Hunyadi L, Sundman E. PetVivo, Inc., Study #PVE122021